Water-Based Black Phosphorus Hybrid Nanosheets as a Moldable Platform for Wound Healing Applications

作者:Huang, Xiao-Wei; Wei, Jing-Jing; Zhang, Meng-Ya; Zhang, Xue-Liang; Yin, Xiao-Fei; Lu, Chun-Hua; Song, Ji-Bin; Bai, Shu-Meng*; Yang, Huang-Hao*
来源:ACS Applied Materials & Interfaces, 2018, 10(41): 35495-35502.
DOI:10.1021/acsami.8b12523

摘要

Black phosphorus (BP) nanosheets with unique biocompatibility and superior optical performance have attracted enormous attention in material science. However, their instability and poor solution-processability severely limit their clinical applications. In this work, we demonstrate the use of silk fibroin (SF) as an exfoliating agent to produce thin-layer BP nanosheets with long-term stability and facile solution-processability. Presence of SF prevents rapid oxidation and degradation of the resultant BP nanosheets, enhancing their performance in physiological environment. The SF-modified BP nanosheets exhibit subtle solution-processability and are fabricated into various BP-based material formats. As superior photothermal agents, BP-based wound dressings effectively prevent bacterial infection and promote wound repair. Therefore, this work opens new avenues for unlocking current challenges of BP nanosheet applications for practical biomedical purposes.