A Convenient Formylation of 2-(Dibromomethyl)-6,11-diphenyl-5,12-naphthacenequinone Using N,N-Dimethylformamide or N,N-Dimethylacetamide: Synthesis of 2-Formyl Rubrene

作者：Wang Yongfei; Zhao Hongbin; Hu Zhizhi^*; Kimura Masaru; Zhang Zhiqiang; Peng Lei; Hiratsuka Koji

来源：Synthesis, 2011, (2): 287-291.

DOI：10.1055/s-0030-1258362

• 2-formyl rubrene
• aldehyde
• formylation
• N,N-dimethylformamide
• N,N-dimethylacetamide

The main objective of this study is the synthesis of 2-formyl rubrene (5,6,11,12-tetraphenyltetracene-2-carbaldehyde). A smooth and efficient method for the formylation of 2-(dibromomethyl)-6,11-diphenyltetracene-5,12-dione is described using N,N-dimethylformamide or N,N-dimethylacetamide as both the formylating agent and solvent, without any additional base. The product, 5,12-dioxo-6,11-diphenyl-5,12-dihydrotetracene-2-carbaldehyde is obtained in quantitative yield and is converted into the target compound via three additional steps.

• 出版日期2011-1
• 单位辽宁科技大学