A new menthane-type monoterpenoid from fermented Illigera aromatica with Clonostachys rogersoniana 828H2

作者:Dong, Jian-Wei; Cai, Le*; Li, Xue-Jiao; Shi, Ya-Xian; Wang, Jia-Peng; Mei, Rui-Feng; Ding, Zhong-Tao*
来源:Journal of Asian Natural Products Research, 2019, 21(7): 673-678.
DOI:10.1080/10286020.2018.1467403

摘要

A new menthane-type monoterpenoid, illigerate E (1), as well as two known ones, (1R*,3R*,4S*,6R*)-6,8-dihydroxymenthol (2) and cis-4-hydroxy-5-(1-hydroxy-1-methylethyl)-2-methyl-2-cyclohexene-1-one (3), were isolated from fermented Illigera aromatica with Clonostachys rogersoniana 828H2. Their structures were identified by HRESIMS and 1D/2D NMR spectra. Their inhibitory effects of NO production in RAW 264.7 macrophages were estimated. [GRAPHICS] .