Anomalous adsorption of biomolecules on a Zn-based metal-organic framework obtained via a facile room-temperature route

作者：Vinogradov Alexandr V^*; Zaake Hertling Haldor; Drozdov Andrey S; Loennecke Peter; Seisenbaeva Gulaim A; Kessler Vadim G; Vinogradov Vladimir V; Hey Hawkins Evamarie

来源：Chemical communications, 2015, 51(100): 17764-17767.

DOI：10.1039/c5cc07808c

Herein, we report a new method for the crystal growth of two Zn-based MOFs at room temperature (known MOF-5 and a new modification of [{Zn-2(TBAPy)(H2O)(2)}center dot 3.5DEF](n) (1)) by employing slow diffusion conditions. Employing both Zn-based MOFs with different pore morphology made it possible to discover an anomalous adsorption of L-histidine in 1 of up to 24.3 x 10(15) molecules cm(-2) at 25 degrees C. This is one of the first reports aimed not only at describing a new method for the targeted formation of crystalline MOFs and coordination polymers, but also at demonstrating the use of Zn-based MOFs as potential drug delivery materials, with highly effective adsorption of L-histidine given herein as an example.

• 出版日期2015