A Chromone from Seseli praecox (Apiaceae)

作者:Leonti Marco*; Casu Laura; Solinas Maria Novella; Cottiglia Filippo; Caboni Pierluigi; Floris Costantino; Gertsch Juerg; Saba Anna Rita
来源:Natural Product Communications, 2010, 5(4): 551-554.

摘要

Chemical investigation of the stems of Seseli praecox (Gamisans) Gamisans, an endemic Apiaceae from Sardinia, afforded an isopropenylated chromone (5-hydroxy-6-(2-Z-butenyl-3-hydroxymethyl)-7-methoxy-2-methylchromone), along with four known linear furocoumarins and their natural precursor. For biological characterization the new compound was screened against four cancer cell lines in vitro and showed differential mu M antiproliferative effects between suspension and adherent cells.

  • 出版日期2010-4