A Facile Synthesis of alpha-Fluoro Ketones Catalyzed by [Cp*IrCl2](2)

作者：Ahlsten Nanna; Bartoszewicz Agnieszka; Agrawal Santosh; Martin Matute Belen^*

来源：Synthesis, 2011, (16): 2600-2608.

DOI：10.1055/s-0030-1260130

• iridium
• fluorine
• isomerization
• alcohols
• fluoro ketones

Allylic alcohols are isomerized into enolates (enols) by [Cp*IrCl2](2). The enolates react with Selectfluor present in the reaction media. This method produces alpha-fluoro ketones as single constitutional isomers in high yields.

• 出版日期2011-8