An alerting structure: human orexin receptor 1

作者：Wacker Daniel; Roth Bryan L^*

来源：Nature Structural & Molecular Biology, 2016, 23(4): 265-266.

DOI：10.1038/nsmb.3198

Structures of the human orexin receptor 1 (hOX(1)R) bound to a selective drug and the dual (hOX(1)R- and hOX(2)R-targeting) antagonist suvorexant reveal molecular mechanisms of selectivity in orexin-receptor subtypes.

• 出版日期2016-4