Medication use associated with exposure to manganese in two Ohio towns

作者：Bowler Rosemarie M^*; Adams Shane W; Wright Chris W; Kim Yangho; Booty Andrew; Colledge Michelle; Gocheva Vihra V; Lobdell Danelle T

来源：International Journal of Environmental Health Research, 2016, 26(5-6): 483-496.

DOI：10.1080/09603123.2016.1194381

• Air
• heavy metals
• illness
• pollution
• communities

This report describes the use of medications as a proxy when medical record reviews are unavailable, to study the health effects of residents environmentally exposed to air-manganese (n=185) compared to unexposed residents (n=90). Participants' current medication lists and medication questionnaire responses were collected in clinical interviews and categorized into 13 domains. Exposed participants reported fewer hours of sleep than controls (6.6 vs. 7.0). The exposed used significantly more medications than unexposed participants (82.2% vs. 67.8%) and, when adjusting for age, education, and personal income, also for pain (aOR=2.40) and hypothyroidism (aOR=7.03). Exposed participants with higher air-Mn concentrations, monitored for 10years by the U.S. Environmental Protection Agency, were 1.5 times more likely to take pain medications. The exposed participants take significantly more medications than unexposed participants in the categories of hypothyroidism, pain, supplements, and total medications.

• 出版日期2016-12