Antibodies as target for affinity biosensors

作者:Patris Stephanie; Vandeput Marie; Kauffmann Jean Michel
来源:TrAC-Trends in Analytical Chemistry, 2016, 79: 239-246.
DOI:10.1016/j.trac.2015.12.005

摘要

Antibodies or immunoglobulins (Ig) are proteins produced by the immune system to protect the body by identifying and neutralizing pathogens. The determination of antibodies is an important area in bioanalysis because their presence provides information about pathologies such as infections, allergies, auto-immune diseases and cancers. Antibodies can be readily detected and quantified by using immunosensors. This review provides an up-to-date overview of immunosensors for the determination of antibodies which can be implemented in the clinical area, for point-of care applications or in routine laboratories.

  • 出版日期2016-5