A novel bis(pinacolato)diboron-mediated N-O bond deoxygenative route to C6 benzotriazolyl purine nucleoside derivatives

作者:Basava Vikram; Yang Lijia; Pradhan Padmanava; Lakshman Mahesh K
来源:ORGANIC %26 BIOMOLECULAR CHEMISTRY, 2016, 14(29): 7069-7083.
DOI:10.1039/c6ob01170e

摘要

O 6-(Benzotriazol-1-yl)purine nucleosides, containing a C–O–N bond, undergo facile reduction of the N–O bond with (pinB)2 and Cs2CO3. Via this approach a series of 6-(benzotriazol-1-yl)purine nucleosides were synthesized and the mechanism has been investigated.

  • 出版日期2016
  • 单位The City College of New York

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