A thin poly(acridine orange) film containing reduced graphene oxide for voltammetric simultaneous sensing of ascorbic acid and uric acid

作者：Tian Li^*; Zhang Boxun; Sun Ding; Chen Ruizhan; Wang Binbin; Li Tianjiao

来源：Microchimica Acta, 2014, 181(5-6): 589-595.

DOI：10.1007/s00604-013-1152-y

• Reduced graphene oxide
• Poly (acridine orange)
• Ascorbic acid
• Uric acid

We have fabricated, in a single step, carbon ceramic electrodes modified with a poly(acridine orange) film containing reduced graphene oxide. They display electrocatalytic activity to ascorbic acid (AA) and uric acid (UA) at pH 4.5. The anodic peak potentials of AA and UA are separated by 276 mV so that they can be well resolved in cyclic voltammetry. UA and AA were simultaneously determined in a mixture at working potentials of 170 and 400 mV, respectively. Under optimized conditions, the calibration curves for AA and UA cover the 0.8-5,000 mu M and 0.6-900 mu M concentration range, respectively, while detection limits are 0.3 mu M and 0.2 mu M. The electrode was applied to determine AA and UA in urine samples.

• 出版日期2014-4
• 单位长春师范大学