A facile method for the rapid and selective deprotection of methoxymethyl (MOM) ethers

作者:Han Jae Hyun; Kwon Young Eun; Sohn Jeong Hun*; Ryu Do Hyun
来源:Tetrahedron, 2010, 66(9): 1673-1677.
DOI:10.1016/j.tet.2010.01.007

摘要

We describe a rapid and efficient method for selective deprotection of methoxymethyl (MOM) ethers using ZnBt(2) and n-PrSH, which completely removed MOM from diverse MOM ethers of primary, secondary. and tertiary alcohols or phenol derivatives The deprotection takes less than ten minutes with both high yield and selectivity in the presence of other protecting groups In addition, the

  • 出版日期2010-2-27