科研之友
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摘要
A new strategy for the synthesis of N-alkoxycarbonyl aryl a-imino esters in the presence of dirhodium tetraacetate [Rh2(OAc)4] is reported to produce the desired compounds in high yield (up to 96%) under mild reaction conditions. The application of the synthetic method is demonstrated in enantioselective reduction and FriedelCrafts reaction of indoles to afford the corresponding chiral arylglycines and indole derivatives, respectively, in high yield and excellent ee.
- 出版日期2012-2
- 单位华东师范大学
