A coumarin-thiourea conjugate as a fluorescent probe for Hg(II) in aqueous media with a broad pH range 2-12

作者：Shiraishi Yasuhiro^*; Sumiya Shigehiro; Hirai Takayuki

来源：Organic and Biomolecular Chemistry, 2010, 8(6): 1310-1314.

DOI：10.1039/b924015b

A coumarin-thiourea conjugate (1) behaves as a highly selective fluorescent probe for Hg(2+) in aqueous media. The probe 1 shows selective and quantitative fluorescence decrease upon Hg(2+) addition in aqueous media with a broad pH range, 2-12. Ab initio molecular orbital calculations reveal that the fluorescence decrease of 1 upon Hg(2+) addition is promoted by a Hg(2+)-induced desulfurization of the thiourea moiety, leading to a decrease in an intramolecular charge transfer (ICT) character of the excited-state coumarin moiety.

• 出版日期2010-3-21