Novel Synthetic Approaches to (Trifluoromethyl)triazoles

作者:Sibgatulin Dmytriy A; Bezdudny Andrii V; Mykhailiuk Pavel K*; Voievoda Nataliia M; Kondratov Ivan S; Volochnyuk Dmitry M; Tolmachev Andrey A
来源:Synthesis (Germany), 2010, 2010(7): 1075-1077.
DOI:10.1055/s-0029-1218656

摘要

New synthetic procedures for the trifluoromethyl-substituted triazoles, 3-(trifluoromethyl)-4H-1,2,4-triazole and 4-(trifluoromethyl)-1H-1,2,3-triazole, have been elaborated. The target compounds were prepared from commercially available trifluoro-acethydrazide (one step) and methyl propiolate (three steps), respectively.

  • 出版日期2010-4