Meaning of Free Intraperitoneal Fluid in Small-Bowel Obstruction Preliminary Results Using High-Frequency Microsonography in a Rat Model

作者：Iacobellis Francesca; Berritto Daniela; Belfiore Maria Paola; Di Lanno Imma; Maiorino Manuela; Saba Luca^*; Grassi Roberto

来源：Journal of Ultrasound in Medicine, 2014, 33(5): 887-893.

DOI：10.7863/ultra.33.5.887

• animal model
• basic science
• free peritoneal fluid
• gastrointestinal ultrasound
• high-frequency sonography
• small-bowel obstruction
• small-animal imaging

Objectives-The aim of this study was to detect the onset, evolution, and meaning of extraluminal free fluid in a rat model of small-bowel obstruction using high-frequency microsonography. %26lt;br%26gt;Methods-Small-bowel obstruction was surgically created in 8 rats divided into 2 groups of 4 rats each. All rats were examined by high-frequency microsonography to monitor the evolution of small-bowel obstruction and the abdominal sonographic findings. In group 2 rats, the obstruction was resolved 2 hours after surgery. %26lt;br%26gt;Results-In all rats, free peritoneal fluid was detected just near the obstructed loop after 1 hour and in the hepatorenal recess after 2 hours. These features progressively increased in the following hours in group 1 rats. In group 2, the amount of free fluid decreased shortly after removing the obstruction. %26lt;br%26gt;Conclusions-Free fluid is an early finding in small-bowel obstruction, and the increase or decrease of its amount is correlated with the worsening or resolution of the obstruction.

• 出版日期2014-5