A Systematic Review of the Clinimetric Properties of the 6-Item Version of the Hamilton Depression Rating Scale (HAM-D-6)

作者：Timmerby N; Andersen J H; Sondergaard S; Ostergaard S D; Bech Per^*

来源：Psychotherapy and Psychosomatics, 2017, 86(3): 141-149.

DOI：10.1159/000457131

• 6-Item Hamilton Depression Rating Scale
• Systematic literature review
• Depression rating scale
• Clinimetrics
• Antidepressant medication

Background: In a study aimed at identifying the items carrying information regarding the global severity of depression, the 6-item Hamilton Depression Rating Scale (HAM-D-6) was derived from the original 17-item version of the scale (HAM-D-17). Since then, the HAM-D-6 has been used in a wide range of clinical studies. We now provide a systematic review of the clinimetric properties of HAM-D-6 in comparison with those of HAM-D-17 and the Montgomery Asberg Depression Rating Scale (MADRS). Methods: We conducted a systematic search of the literature in PubMed, Psyclnfo, and EMBASE databases in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guideline. Studies reporting data on the clinimetric validity of the HAM-D-6 and either the HAM-D-17 or MADRS in non-psychotic unipolar or bipolar depression were included in the synthesis. Results: The search identified 681 unique records, of which 51 articles met the inclusion criteria. According to the published literature, HAM-D-6 has proven to be superior to both HAM-D-17 and MADRS in terms of scalability (each item contains unique information regarding syndrome severity), transferability (scalability is constant over time and irrespective of sex, age, and depressive subtypes), and responsiveness ( sensitivity to change in severity during treatment). Conclusions: According to the published literature, the clinimetric properties of HAM-D-6 are superior to those of both the HAM-D-17 and MADRS. Since the validity of HAM-D-6 has been demonstrated in both research and clinical practice, using the scale more consistently would facilitate translation of results from one setting to the other.

• 出版日期2017
• 单位上海市精神卫生中心