Weight control in occupational subjects: efficacy of a natural vegetarian replacement raw meal included in a moderately low-calorie-diet

作者：Vigna L^*; Cossovic A; Sommaruga D; De Giuseppe R; de Liso F; Novembrino C; Tirelli A S; Maiavacca R; Bamonti F

来源：Progress in Nutrition, 2012, 14(4): 265-276.

• oxidative stress
• vegetarian row meal
• meal replacement
• overweight
• obesity
• occupational subjects

As is well known, obesity often leads to insulin resistance, dyslipidemia, and oxidative stress contributing to cardiovascular diseases. A change in lifestyle could reduce obesity-related risk factors with, for example, short lunch breaks, nowadays more frequently prescribed as meal replacements by doctors. GoJuvo(R) is a new commercial plant-based vegetarian meal with low glycaemia index food. Very few data are available on its metabolic effects; our aim was to verify, by assessing nutritional parameters, if GoJuvo(R) nutritional claims were confirmed by scientific tests. Thirty four occupational overweight-obese subjects%26apos; anthropometric parameters, glycaemia status, lipid panel and oxidative status (Reactive Oxygen Species, ROS; Total Antioxidant Capacity, TAC; oxidized LDL, ox-LDL) were evaluated at baseline (T0); after 1 month%26apos;s GoJuvo(R) diet-therapy included in a moderately low-calorie-diet program, only anthropometric parameters were re-evaluated. At T0 HOMA-IR index was slightly above average with high inter-individual variability; the majority of subjects%26apos; oxidative status was altered without dyslipidemia. The use of GoJuvo(R) as an alternative to meals, associated with a diet low in calories and slightly higher in proteins, helped reduce weight by 4.6%, BMI by 4.2%, waist circumference by 2.9%. According to our study, GoJuvo(R) plays a more important role in controlling hunger, satiety and food intake of calories than a traditional meal. Due to the short duration of GoJuvo(R) treatment (1 month), we could not ascertain whether its fibre content also modulates the metabolic indices associated with type2 diabetes development and possible anti-oxidant effect. Interestingly, all subjects lost a significant amount of weight and, as a result, their physical appearance and lifestyle improved significantly.

• 出版日期2012