Activity of telavancin compared to other agents against coagulase-negative staphylococci with different resistotypes by time kill

作者：Lin Gengrong; Pankuch Glenn A; Appelbaum Peter C; Kosowska Shick Klaudia^*

来源：Diagnostic Microbiology and Infectious Disease, 2012, 73(3): 287-289.

DOI：10.1016/j.diagmicrobio.2012.04.003

• Telavancin
• Staphylococcus aureus
• Time kill

Among 10 coagulase-negative staphylococci, telavancin, quinupristin/dalfopristin, and tigecycline were the most potent antimicrobials. Telavancin exhibited bactericidal effect to 9 strains out of 10 tested at 4x MIC after 24 h of exposure similar to those of vancomycin and daptomycin. By contrast, linezolid was mainly bacteriostatic and teicoplanin was bactericidal to 7 strains tested at 4x MIC after 24 h.

• 出版日期2012-7