A Tf-Independent Iron Transport System Required for Organogenesis

作者：Troadec Marie Berengere; Ward Diane M; Kaplan Jerry^*

来源：Developmental Cell, 2009, 16(1): 3-4.

DOI：10.1016/j.devcel.2008.12.013

Cells require iron as a cofactor for proteins that are essential for growth. While delivery of iron to cells by transferrin is well known, Li et al. in this issue of Developmental Cell show that ferritin, through its binding to the cell surface Scara5 receptor, can also deliver iron to cells, permitting kidney organogenesis.

• 出版日期2009-1-20