A Novel Tool in Laryngeal Surgery: Preliminary Results of the Picosecond Infrared Laser

作者：Boettcher Arne; Clauditz Till S; Knecht Rainald; Kucher Stanislav; Woellmer Wolfgang; Wilczak Waldemar; Kroetz Peter; Jowett Nathan; Dalchow Carsten V; Muenster Adrian; Miller R J Dwayne

来源：Laryngoscope, 2013, 123(11): 2770-2775.

DOI：10.1002/lary.24124

• Larynx surgery
• laser
• PIRL
• histology
• damage zone
• laryngeal surgery
• laser
• PIRL
• CO2
• damage zone

Objectives/HypothesisConventional lasers ablate tissue through photothermal, photomechanical, and/or photoionizing effects, which may result in collateral tissue damage. The novel nonionizing picosecond infrared laser (PIRL) selectively energizes tissue water molecules using ultrafast pulses to drive ablation on timescales faster than energy transport to minimize collateral damage to adjacent cells.
Study DesignAnimal cadaver study.
MethodsCuts in porcine laryngeal epithelium, lamina propria, and cartilage were made using PIRL and carbon dioxide (CO2) laser. Lateral damage zones and cutting gaps were histologically compared.
ResultsThe mean widths of epithelial (8.5 m), subepithelial (10.9 m), and cartilage damage zones (8.1 m) were significantly lower for cuts made by PIRL compared with CO2 laser (p < 0.001). Mean cutting gaps in vocal fold (174.7 m) and epiglottic cartilage (56.3 m) were significantly narrower for cuts made by PIRL compared with CO2 laser (P < 0.01, P < 0.05).
ConclusionPIRL ablation demonstrates superiority over CO2 laser in cutting precision with less collateral tissue damage.
Level of EvidenceN/A. Laryngoscope, 123:2770-2775, 2013

• 出版日期2013-11