Ultrasound-Guided Diffuse Optical Tomography for Predicting and Monitoring Neoadjuvant Chemotherapy of Breast Cancers: Recent Progress

作者：Xu Chen; Vavadi Hamed; Merkulov Alex; Li Hai; Erfanzadeh Mohsen; Mostafa Atahar; Gong Yanping; Salehi Hassan; Tannenbaum Susan; Zhu Quing^*

来源：Ultrasonic Imaging, 2016, 38(1): 5-18.

DOI：10.1177/0161734615580280

• near infrared imaging
• ultrasound-guided optical imaging
• ultrasound
• breast cancer treatment monitoring
• dual-modalities

In this manuscript, we review the current progress of utilizing ultrasound-guided diffuse optical tomography (US-guided DOT) for predicting and monitoring neoadjuvant chemotherapy (NAC) outcomes of breast cancer patients. We also report the recent advance on optical tomography systems toward portable and robust clinical use at multiple clinical sites. The first patient who has been closely monitored before NAC, at day 2, day 8, end of first three cycles of NAC, and before surgery is given as an example to demonstrate the potential of US-guided DOT technique.

• 出版日期2016-1