Utilization of Potassium Vinyltrifluoroborate in the Development of a 1,2-Dianion Equivalent

作者：Molander Gary A^*; Sandrock Deidre L

来源：Organic Letters, 2009, 11(11): 2369-2372.

DOI：10.1021/ol900822j

Previous studies of orthogonally reactive dibora species led to the discovery of a unique reactivity pattern associated with potassium vinyltrifluoroborate. Upon hydroboration, the vinyltrifluoroborate generates a 1,2-diboraethane, which is distinct from the 1,1-dibora intermediates generated when traditional alkenyldialkylboron species undergo hydroboration. The 1,2-dianion equivalent thus generated can be envisioned as a building block for the linkage of two different electrophiles via palladium-catalyzed Suzuki-Miyaura cross-couplings.

• 出版日期2009-6-4