Dosimetric optimization of a colpostat in a Co-60 high-dose-rate brachytherapy unit for bladder sparing

作者：Zakariaee Seyed Salman; Mandavi Seied Rabi^*

来源：Brachytherapy, 2015, 14(1): 37-45.

DOI：10.1016/j.brachy.2014.08.049

• GZP6 HDR system
• HDR Co-60 brachytherapy source
• Monte Carlo simulation
• Bladder sparing

BACKGROUND: Cervical cancer brachytherapy has an effective role on the tumor control probability as a boost and/or single treatment option. High-dose-rate Co-60 brachytherapy units are used in many radiation oncology centers in Iran. Rectum and bladder tissues are considered as organs at risk in radiation treatment of cervical cancers, and they should be spared from unwanted radiation risk.
PURPOSE: In the present study, the effect of additional tungsten shield was investigated in a new colpostat design for bladder protection against radiation.
METHODS AND MATERIALS: Monte Carlo (MC) simulation has been performed using the MC N-Particle eXtended version 2.4.0 transport code. The HDR GZP6 brachytherapy source applicator was simulated along with its colpostats. The f6 tally was used for absorbed dose calculation; and for model validation, we used from dosimetric features of the GZP6 treatment planning system.
RESULTS: Results calculated by MC simulation method showed that dose reduction at the end of the colpostat was 2.44% for the medium colpostat and a dose increase of 1.35% was obtained for the small colpostat. In the reference point of the bladder (at the distance 1 cm from the end point of the colpostat), the percentages of dose reductions were also 25% and 15% for medium and small colpostats, respectively.
CONCLUSIONS: Results show that the absorbed dose in the bladder tissue can be reduced significantly using a shielded colpostat.

• 出版日期2015-2