Association between Schistosomiasis mansoni and hepatitis C: systematic review

作者：de Moraes Van Lume Daniele Silva; Pessoa Militao de Albuquerque Maria de Fatima; de Souza Alexandre Ignacio; Coutinho Domingues Ana Lucia; de Almeida Lopes Edmundo Pessoa; Lins de Morais Clarice Neuenschwander; Lucena Montenegro Silvia Maria

来源：Revista de Saude Publica, 2013, 47(2): 414-424.

DOI：10.1590/S0034-910.2013047004247

• Comorbidity
• Hepatitis C, epidemiology
• Schistosomiasis, epidemiology
• Review

OBJECTIVE: To perform a systematic review of the prevalence of the HCV/S. mansoni co-infection and associated factors in Schistosoma mansoni-infected populations. %26lt;br%26gt;METHODS: The bibliographic search was carried out using the Medline, Lilacs, SciELO, Cochrane Library and Ibecs databases. The criteria for the studies%26apos; selection and the extraction data were based on systematic review methods. Forty five studies were found, with nine being excluded in a first screening. Thirteen articles were used for data extraction. %26lt;br%26gt;RESULTS: The HCV infection rates in schistosomiasis populations range from 1% in Ethiopia to 50% in Egypt. Several studies had poorly defined methodologies, even in areas characterized by an association between hepatitis C and schistosomiasis, such as Brazil and Egypt, which meant conclusions were inconsistent. HCV infection rates in schistosomotic populations were heterogeneous and risk factors for acquiring the virus varied widely. %26lt;br%26gt;CONCLUSIONS: Despite the limitations, this review may help to identify regions with higher rates of hepatitis C and schistosomiasis association. However, more studies are necessary for the development of public health policies on prevention and control of both diseases.

• 出版日期2013-4