A new furanocoumarin from the roots of Angelica oncosepala

作者:Zheng, Bin*; Qing, Chen; Wang, Ji-Liang; Tang, Li-Ping; Li, Xian
来源:Chemistry of Natural Compounds, 2012, 48(5): 748-750.
DOI:10.1007/s10600-012-0373-3

摘要

A new furanocoumarin oncosepalin A (1), together with two known compounds, ferulic acid and beta-sitosterol, was isolated from the roots of Angelica oncosepala. The structure of the new compound was elucidated by spectroscopic methods, including extensive 1D and 2D NMR experiments, as well as high-resolution EI mass analysis. Compound 1 showed cytotoxic inhibition against HL-60 human tumor cell lines with an IC50 value of 2.04 mu M.

全文