New labdane diterpenes from Solidago canadensis

作者：Wangensteen Helle^*; Phan Thi T; Rise Frode; Halvorsen Trine G; Malterud Karl E

来源：Natural Product Research, 2012, 26(14): 1348-1354.

DOI：10.1080/14786419.2011.565005

• Solidago canadensis
• Asteraceae
• Canadian goldenrod
• labdane diterpenes

The ethanol extract of roots of Solidago canadensis yielded eight labdane-type diterpenes. Five of those were new natural compounds (9,13,15,16-bisepoxy-labdane-7-ene-6,15-dione (3a), 13-epi-9,13,15,16-bisepoxy-labdane-7-ene- 6,15-dione (3b), 15,16-epoxy-labdane-7,13-diene-6,16-dione (5), 15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6a) and 13-epi-15-ethoxy-9,13,15,16-bisepoxy-labdane-7-ene-6-one (6b). The known labdane diterpenes deoxysolidagenone (1), solidagenone (2) and 15,16-epoxy-labdane-7,13-diene-6,15-dione (4) were also isolated. Chemical structures were determined using 1D and 2D NMR techniques and MS analysis.

• 出版日期2012