Microstructural parcellation of the human cerebral cortex - from Brodmann's post-mortem map to in vivo mapping with high-field magnetic resonance imaging

作者：Geyer Stefan^*; Weiss Marcel; Reimann Katja; Lohmann Gabriele; Turner Robert

来源：Frontiers in Human Neuroscience, 2011, 5: 19.

DOI：10.3389/fnhum.2011.00019

• brain map
• cortical areas
• cytoarchitecture
• myeloarchitecture
• quantitative T1 map

The year 2009 marked the 100th anniversary of the publication of the famous brain map of Korbinian Brodmann. Although a "classic" guide to microanatomical parcellation of the cerebral cortex, it is - from today's state-of-the-art neuroimaging perspective - problematic to use Brodmann's map as a structural guide to functional units in the cortex. In this article we discuss some of the reasons, especially the problematic compatibility of the "post-mortem world" of microstructural brain maps with the "in vivo world" of neuroimaging. We conclude with some prospects for the future of in vivo structural brain mapping: a new approach which has the enormous potential to make direct correlations between microstructure and function in living human brains: "in vivo Brodmann mapping" with high-field magnetic resonance imaging.

• 出版日期2011-2-18