A heterogeneous gold(I)-catalyzed ring expansion of unactivated alkynylcyclopropanes with sulfonamides leading to (E)-2-alkylidenecyclobutanamines

作者：Yi, Feiyan; Huang, Bin; Nie, Quan; Cai, Mingzhong^*

来源：Tetrahedron Letters, 2016, 57(39): 4405-4410.

DOI：10.1016/j.tetlet.2016.08.062

• Gold
• Ring expansion
• Four-membered carbocycle
• Magnetic nanoparticle
• Heterogeneous catalysis

A heterogeneous gold(I)-catalyzed ring expansion of unactivated alkynylcyclopropanes was achieved in 1,2-dichloroethane at 100 degrees C in the presence of sulfonamides by using a magnetic nanoparticle-supported phosphine gold(I) complex [Fe3O4@SiO2-P-AuOTf] as catalyst, yielding a variety of (E)-2-alkyli-denecyclobutanamines in moderate to high yields. The new heterogeneous gold catalyst can easily be separated from the reaction mixture by applying an external magnet and recycled at least 10 times without a significant loss of activity.

• 出版日期2016-9-28
• 单位江西师范大学