A Green and Efficient Synthesis of 3,3 '-Arylidenebis[4-hydroxy-6-methyl-2(1h)-3-pyridinone]s in Water under Microwave Irradiation

作者：Shi Feng; Cao Longji; Ma Ning; Zhang Ge; Chen Rongshun; Zhang Yajie; Tu Shujiang^*

来源：Journal of Heterocyclic Chemistry, 2010, 47(1): 22-25.

DOI：10.1002/jhet.210

A series of 3,3'-arylidenebis[4-hydroxy-6-methyl-2(1H)-3-pyridinone]s were synthesized via three-component reactions of aromatic aldehydes, 4-hydroxy-6-methyl-2H-pyran-2-one, and ammonium acetate in water under microwave irradiation. This method has the advantages of environmental friendliness, short reaction time, high yields, and easy operation. This efficient synthesis not only offers an economical and green synthetic strategy to this class of significant compounds but also enriches the investigations on microwave-assisted synthesis in water.

• 出版日期2010-1
• 单位江苏师范大学