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摘要
A new iodonium ylide-based three-component reaction for the synthesis of highly functionalized 2-spirosubstituted dihydrofurans starting from readily available common reactants has been developed under microwave irradiation. The procedure is facile, avoiding time-consuming and costly syntheses, tedious work-up and purifications of precursors as well as protection/deprotection of functional groups. This method is very efficient because of short reaction times and easy work-up and provides an efficient strategy for the construction of the polysubstituted spiro dihydrofuran skeleton.
- 出版日期2014-3
