摘要

Cardiovascular diseases (CVD) account for high morbidity all over the world; risk factors include age, sex, hypertension, smoking, diabetes, high LDL and low HDL cholesterol levels. Elevated Lipoprotein (a) is an emerging independent risk factor in the development of cardiovascular diseases. Biochemical analysis revealed that 62.5 % of the subjects had elevated Lp(a) levels and 75 % of the subjects had elevated Homocysteine levels indicating their being at higher risk of CVD. Increased knowledge of the role of Lp(a) as a risk factor for CHD would be of great benefit. Because Lp(a) is genetically determined, we also recommend further studies to examine the relationship between family history of CHD and Lp(a) levels.
Homocysteine levels in all the subjects were also found to be high. Dietary survey revealed a high intake of total fat, low intake of fiber and the P/S ratio indicated a higher consumption of saturated fats. Reducing serum homocysteine levels can reduce the risk of CVD which can be achieved by increasing the consumption of folic acid. Thus high risk subjects need nutrition education to control these risk factors for the prevention of this major disease.

  • 出版日期2013-12