The study on the possible relationship between the residual bone cement in vertebral pedicle and the prognosis of osteoporotic vertebral compression fractures

作者：Yan, Suozhou; Wang, Xiaoyu; Di, Jun; Yang, Sidong; Kong, Lingde; Li, Jia; Ding, Wenyuan; Shen, Yong^*

来源：International Journal of Clinical and Experimental Medicine, 2017, 10(6): 9476-9481.

• Osteoporotic vertebral compression fractures
• bone cement
• percutaneous vertebroplasty
• postoperative low back pain

Objective: To explore possible relationship between the residual bone cement in vertebral pedicle and the prognosis of osteoporotic vertebral compression fractures in patients who were treated with percutaneous vertebroplasty. Methods: A total of 100 patients admitted to our hospital from January 2013 to December 2016, who had low back pain in different degrees after treated with percutaneous vertebroplasty for osteoporotic vertebral compression fractures during one-year follow-up, were selected as subjects. Those patients were divided into the slight pain group (SliP group) (0-3 points) and the severe pain group (SevP group) (4-10 points) according to the postoperative VAS scores, and each group included 50 cases. The pain degrees of the patients in two groups were assessed and compared using the visual analog scale (VAS), the CT scan was performed to the medial and lateral vertebral pedicle for marking bone cement residue (BCR) and the scores were compared. Meanwhile, Pearson methods were also performed to analyze the relationship between BCR scores and the VAS scores. And the recurrences and the hospitalization of patients were compared between these two groups. Results: Before operation, there is no significant difference in the VAS scores between two groups. After operation, the VAS score of SliP group (2.23 +/- 0.87) was significantly lower than that in the SevP group (4.48 +/- 0.91) (P<0.05) and the difference was statistically significant. The BCR scores in medial and lateral vertebral pedicle in SliP group (0.22 +/- 0.06, 0.26 +/- 0.08) were significantly lower than those in SevP group (0.39 +/- 0.13, 0.46 +/- 0.17) (P<0.05). And the BCR scores in medial and lateral vertebral pedicle were positively correlated with postoperative low back pain (r=0.757, 0.773, P=0.011, 0.009). The recurrence (2%) and hospitalization (7.58 +/- 2.54 d) of patients in SliP group were significantly lower than those in SevP group (P<0.05). Conclusion: After percutaneous vertebroplasty, the postoperative VAS scores and recurrences of fracture of osteoporotic vertebral compression fractures were low, the hospitalization of patients was short and the BCR scores in vertebral pedicle were positively correlated with postoperative low back pain. Therefore, we can improve the therapeutic effects and alleviate postoperative low back pain by clearing the BCR away.

• 出版日期2017
• 单位河北医科大学