Antibacterial activity of chitosan coated Ag-loaded nano-SiO2 composites

作者:Niu Mei; Liu Xuguang*; Dai Jinming; Jia Husheng; Wei Liqiao; Xu Bingshe
来源:Carbohydrate Polymers, 2009, 78(1): 54-59.
DOI:10.1016/j.carbpol.2009.04.029

摘要

A crosslinked chitosan (CCTS) coated Ag-loading nano-SiO2 composite (CCTS-SLS) was prepared. The structures of CCTS-SLS were characterized by field emission scanning electron microscopy and X-ray photoelectron spectroscopy. The antibacterial properties of CCTS-SLS were measured as the minimal inhibitory concentration and the rate of bacterial growth. The experimental results indicate that the antibacterial activity of CCTS-SLS was affected by the mass ratio of SLS to chitosan, acetic acid concentration and crosslinking time. Moreover, CCTS-SLS exhibited high antibacterial activity against Escherichia coli and Staphylococcus aureus as a result of the coordinated action of CCTS and SLS.