科研之友
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摘要
The corrole-based catalytic antioxidant 1-Fe reduced the cholesterol biosynthesis ability of macrophages, harvested from mice treated with it. 1-Fe and a non-redox active analogue of it affect the committed step of the biosynthetic pathway - the HMG-CoA reductase catalysed reaction - by acting as allosteric inhibitors of this key enzyme.
- 出版日期2013
