The Cohesin Complex: A Platform for Checkpoint Activation and DNA Repair?

作者:Paschal Catherine R*; Bhalla Needhi
来源:Current Biology, 2011, 21(17): R649-R650.
DOI:10.1016/j.cub.2011.07.039

摘要

In mitosis, the cohesin complex contributes to DNA damage checkpoint activation and repair, presumably by keeping sister chromatids linked to provide a template for repair. A recent study illustrates that this complex plays a similar role during meiosis, even though the preferred partner for meiotic DNA repair is the homologous chromosome.

  • 出版日期2011-9-13