A Chinese pedigree of cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL): Clinical and radiological features

作者：Zheng D M^*; Xu F F; Gao Y; Zhang H; Han S C; Bi G R

来源：Journal of Clinical Neuroscience, 2009, 16(6): 847-849.

DOI：10.1016/j.jocn.2008.08.031

• Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
• Cerebral vascular disease
• MRI

Cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy (CARASIL) is a rare hereditary cerebral vascular disease thought to be confined to Japan. This paper reports a Chinese pedigree of CARASIL in which two patients exhibited all of the typical clinical features of the disease. The radiological features are also discussed and compared with those of CADASIL. These cases illustrate the unique clinical and radiological features of CARASIL and challenge the idea that CARASIL is limited to the Japanese Population.

• 出版日期2009-6
• 单位中国医科大学