科研之友
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摘要
A tetranor-cycloartane glycoside and two 9,19-cycloartane glycosides were isolated from the EtOAc-soluble fraction of the rhizome of Cimicifuga foetida. The structures of the compounds were determined to be cimilactone A (1), 25-O-acetylcimigenol 3-O-beta-D-xylopyranoside (2) and cimigenol 3-O-alpha-L-arabinopyranoside (3), respectively, using spectroscopic analysis. The three compounds were examined for their anticomplement activity against the classical pathway of the complement system. Compound 1 showed significant anticomplement activity with an IC50 value of 28.6 mu m, whereas compounds 2 and 3 were inactive.
- 出版日期2006-11
- 单位中国科学院昆明植物研究所
