Melatonin as a potential tool against oxidative damage and apoptosis in ejaculated human spermatozoa

作者:Espino Javier; Bejarano Ignacio; Ortiz Agueda; Lozano Graciela M; Garcia Juan F; Pariente Jose A; Rodriguez Ana B*
来源:Fertility and Sterility, 2010, 94(5): 1915-1917.
DOI:10.1016/j.fertnstert.2009.12.082

摘要

It is assumed somatic cells can die in the apoptotic, the autophagic, or the necrotic way; however, the mechanisms of sperm death are not clear. Here, ejaculated human spermatozoa were evaluated for apoptosis and reactive oxygen species production in the absence or presence of melatonin, and we concluded that melatonin reverses sperm apoptosis due to its free radical scavenging actions. (Fertil Steril (R) 2010;94:1915-7.

  • 出版日期2010-10