Application of automated peritoneal dialysis in urgent-start peritoneal dialysis patients during the break-in period

作者：Liu, Shengmao; Zhuang, Xiaohua; Zhang, Min; Wu, Yanfeng; Liu, Min; Guan, Sibo; Liu, Shujun; Miao, Lining; Cui, Wenpeng^*

来源：International Urology and Nephrology, 2018, 50(3): 541-549.

DOI：10.1007/s11255-018-1785-1

• Peritoneal dialysis
• Break-in period
• Automated peritoneal dialysis
• Continuous ambulatory peritoneal dialysis

Whether automated peritoneal dialysis (APD) is a feasible strategy for urgent-start peritoneal dialysis (PD) therapy during the break-in period remains unclear. This study was conducted to compare the efficacy as well as complications among three PD modes during the break-in period.
Ninety-six patients treated with urgent-start PD after catheterization were retrospectively analyzed. Patients were divided into three groups, incremental continuous ambulatory PD (CAPD) group (n = 26); APD group (n = 42); and APD-CAPD group (n = 28). Clinical parameters at the end of the break-in period and 1 month after the initiation of PD treatment were collected and analyzed.
Compared with the traditional incremental CAPD, APD and APD-CAPD were superior as they could effectively remove small-molecule uremic toxins and correct electrolyte imbalance (P < 0.05), while did not increase the incidence of early complications during the break-in period (P > 0.05). However, APD led to a significant decline in albumin and pre-albumin, as compared with APD-CAPD and CAPD (P < 0.05). A PD strategy consisting 6 days of APD and 3 days of CAPD showed a great advantage in preventing excessive protein loss. There were no significant differences in all tested biochemical parameters among the three groups at 1 month after treatment (all P > 0.05).
Application of APD for urgent-start PD during the break-in period is feasible. A combination of APD and CAPD regimens seems to be a more reasonable mode.

• 出版日期2018-3
• 单位吉林大学