Antioxidant, phenolic and antifungal profiles of Acanthus mollis (Acanthaceae).

作者：Jara Carlos; Leyton Miguel; Osorio Mauricio; Silva Viviana; Fleming Francisco; Paz Marilyn; Madrid Alejandro; Mellado Marco^*

来源：Natural Product Research, 2017, 31(19): 2325-2328.

DOI：10.1080/14786419.2017.1299726

• Acanthus mollis
• phenolic compounds
• antioxidant activity
• antifungal activity

Acanthus mollis is used as ornamental and medicinal plant. The ethnopharmacology reports indicate that extracts have antiinflammatory activity. Phytoconstituents profile was evaluated by estimating the content of anthraquinones, flavonoids and phenols. In addition, the antioxidant activity was evaluated using four methods: Hydrogen atoms transfer (TRAP, ORAC and DPPH assays), and single electron transfer (FRAP assay). Finally, antifungal activity was determined by the M27-A2 test. The results shown that ethanol extracts have the highest concentration of phenols, anthraquinones and flavonoids. Total antioxidant capacity, extracts of ethyl acetate and ethanol are those with the highest activity, which correlates strongly with the presence of phenols. The antifungal activity measured in various strains of Candida is concentrated in ethyl acetate extracts of flower and leaf ethanol, a phenomenon may be related to antioxidant activity.

• 出版日期2017