Association of Age, Sex, Body Size and Ethnicity with Electrocardiographic Values in Community-based Older Asian Adults

作者：Tan Eugene S J; Yap Jonathan; Xu Chang Fen; Feng Liang; Nyunt Shwe Zin; Santhanakrishnan Rajalakshmi; Chan Michelle M Y; Seow Swee Chong; Ching Chi Keong; Yeo Khung Keong; Richards A Mark; Ng Tze Pin; Lim Toon Wei; Lam Carolyn S P^*

来源：Heart Lung and Circulation, 2016, 25(7): 705-711.

DOI：10.1016/j.hlc.2016.01.015

• Age
• Sex
• Ethnicity
• Body size
• Electrocardiogram
• Asian

Background Existing electrocardiographic (ECG) reference values were derived in middle-aged Caucasian adults. We aimed to assess the association of age, sex, body size and ethnicity on ECG parameters in a multi-ethnic Asian population.
Methods Resting 12-lead ECG and anthropometric measurements were performed in a community-based cohort of 3777 older Asians (age 64.7 +/- 9.1 years, 1467 men, 88.8% Chinese, 7.7% Malay, 3.5% Indian, body mass index [BMI] 24.0 +/- 3.9 kg/m(2)).
Results Men had longer PR interval, wider QRS, shorter QTc interval and taller SV3. In both sexes, older age was associated with longer PR interval, wider QRS, larger R aVL and more leftward QRS axis, while higher BMI was associated with longer PR interval, wider QRS, larger RaVL and more negative QRS axis. There were significant inter-ethnic differences in QRS duration among men, as well as in PR and QTc intervals among women (all adjusted p < 0.05). Findings were similar in a healthy subset of 1158 adults (age 61.2 +/- 9.1 years, 365 men) without cardiovascular risk factors.
Conclusions These first community-based ECG data in multi-ethnic older Asians highlight the independent effects of age, sex, body size and ethnicity on ECG parameters.

• 出版日期2016-7