A new alkylene dihydrofuran glycoside with antioxidation activity from the root bark of Morus alba L.

作者：Fu Wei; Lei Yong Fang; Cai Ya Ling; Zhou Dao Nian; Ruan Jin Lan^*

来源：Chinese Chemical Letters, 2010, 21(7): 821-823.

DOI：10.1016/j.cclet.2010.02.016

• Morus alba L.
• Dihydrofuran glycoside
• Spectral analysis
• Antioxidation activity

A new alkylene dihydrofuran glycoside (1) was isolated from the root bark of Morus alba L., along with moracin M-3'-O-beta-D-glucopyranoside (2), and moracin M-6, 3'-di-O-beta-D-glucopyranoside (3). Compound 1 was identified as 2-methylene-3-methoxy-2,5-dihydrofuran-4-O-beta-D-glucopyranosicle on the basis of chemical and spectroscopic data including 1D and 2D NMR spectral analysis. In addition, the antioxidant activity of 1 was evaluated using the 1,1-dipheny1-2-picrylhydrazyl (DPPH) and 2,2'-azinobis-3-ethylbenzothiazoline-6-sulphonic acid (ABTS) assay. The IC(50) values were 2.49 and 0.45 mg/mL, respectively.

• 出版日期2010-7
• 单位华中科技大学