Access to side-chain carbon information in deuterated solids under fast MAS through non-rotor-synchronized mixing

作者：Kulminskaya Natalia; Vasa Suresh Kumar; Giller Karin; Becker Stefan; Kwan Ann; Sunde Margaret; Linser Rasmus

来源：Chemical Communications, 2016, 52(2): 268-271.

DOI：10.1039/c5cc07345f

We demonstrate the accessibility of aliphatic C-13 side chain chemical shift sets for solid-state NMR despite perdeuteration and fast MAS using isotropic, non-rotor-synchronized C-13-C-13 mixing. Combined with amide proton detection, we unambiguously and sensitively detect whole side chain to backbone correlations for two proteins using around 1 mg of sample.

• 出版日期2016