Neonatal Hemolytic Uremic Syndrome After Mother-to-Child Transmission of a Low-Pathogenic stx2b Harboring Shiga Toxin-Producing Escherichia coli

Stritt Andrea; Tschumi Sibylle; Kottanattu Lisa; Bucher Barbara S; Steinmann Markus; von Steiger Niklaus; Stephan Roger; Haechler Herbert; Simonetti Giacomo D<sup>*</sup>

doi:10.1093/cid/cis851

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Neonatal Hemolytic Uremic Syndrome After Mother-to-Child Transmission of a Low-Pathogenic stx2b Harboring Shiga Toxin-Producing Escherichia coli

作者：Stritt Andrea; Tschumi Sibylle; Kottanattu Lisa; Bucher Barbara S; Steinmann Markus; von Steiger Niklaus; Stephan Roger; Haechler Herbert; Simonetti Giacomo D^*

来源：Clinical Infectious Diseases, 2013, 56(1): 114-116.

DOI：10.1093/cid/cis851

摘要

This case describes evidence for a Shiga toxin-producing Escherichia coli (STEC) O146:H28 infection leading to hemolytic uremic syndrome in a neonate. STEC O146:H28 was linked hitherto with asymptomatic carriage in humans. Based on strain characteristics and genotyping data, the mother is a healthy carrier who transmitted the STEC during delivery. STEC strains belonging to the low-pathogenic STEC group must also be considered in the workup of neonatal hemolytic uremic syndrome.