Adaptive Evolution: Don't Fix What's Broken

作者:Liu Gaowen; Rancati Giulia*
来源:Current Biology, 2016, 26(4): R169-R171.
DOI:10.1016/j.cub.2015.12.029

摘要

Evolution of budding yeast after the removal of an important component of the polarization machinery, BEM1, followed reproducible evolutionary trajectories governed by epistasis. Interestingly, cells restored polarization not by finding a substitute for Bem1 but by rendering its function dispensable.

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