ACUTE KIDNEY INJURY Clinical trials in AKI: is the end in sight?

作者:Parks Monica; Liu Kathleen D*
来源:Nature Reviews Nephrology, 2016, 12(5): 263-264.
DOI:10.1038/nrneph.2016.35

摘要

Clinical trials in patients with acute kidney injury (AKI) have been stymied by a lack of consensus on suitable renal-specific end points. In a recent analysis, Grams et al. suggest that a sustained 30-40% reduction in estimated glomerular filtration rate after hospital discharge might be a suitable intermediate end point for AKI clinical trials.

  • 出版日期2016-5