Comparison of 3D magnetic resonance imaging and digital subtraction angiography for intracranial artery stenosis

作者：Park Ji Eun; Jung Seung Chai^*; Lee Sang Hun; Jeon Ji Young; Lee Ji Ye; Kim Ho Sung; Choi Choong Gon; Kim Sang Joon; Lee Deok Hee; Kim Seon Ok; Kwon Sun U; Kang Dong Wha; Kim Jong S

来源：European Radiology, 2017, 27(11): 4737-4746.

DOI：10.1007/s00330-017-4860-6

• Intracranial stenosis
• Magnetic resonance imaging
• Angiography
• Diagnosis
• Stenosis

Objectives To compare three-dimensional high-resolution magnetic resonance imaging (3D HR-MRI) and digital subtraction angiography (DSA) for diagnosing and evaluating stenosis in the entire circle of Willis.
Methods The study included 516 intracranial arteries from 43 patients with intracranial artery stenosis (ICAS) who underwent both 3D HR-MRI and DSA within 1 month. Two readers independently diagnosed atherosclerosis, dissection, moyamoya disease and vasculitis, rated their diagnostic confidence for each vessel and measured the luminal diameters. Reference standard was made from clinico-radiologic diagnosis. Diagnostic accuracy, diagnostic confidence, the degree of stenosis and luminal diameter were assessed and compared between both modalities.
Results For atherosclerosis, 3D HR-MRI showed better diagnostic accuracy (P = .03-.003), sensitivity (P = .006-.01) and positive predictive value (P <= .001-.006) compared to DSA. Overall, the readers were more confident of their diagnosis of ICAS when using 3D HR-MRI (reader 1, P <= .001-.007; reader 2, P <= .001-.015). 3D HR-MRI showed similar degree of stenosis (P > .05) and higher luminal diameter (P < .05) compared to DSA.
Conclusions 3D HR-MRI might be useful to evaluate atherosclerosis, with better diagnostic confidence and comparable stenosis measurement compared to DSA in the entire circle of Willis.

• 出版日期2017-11