The effect of sleeping with the head of the bed elevated six inches on elderly patients with orthostatic hypotension: an open randomised controlled trial

作者：Fan Chie Wei^*; Walsh Cathal; Cunningham Conal J

来源：Age and Ageing, 2011, 40(2): 187-192.

DOI：10.1093/ageing/afq176

• trials
• haemodynamics
• blood pressure
• elderly

Objective: to investigate the effects of 6-inch SHU for 6 weeks in community-living patients with chronic OH.
Design: open labelled randomised controlled trial.
Methods: one hundred patients aged >= 60 with chronic OH were randomised into SHU or control groups. Primary outcome measures were mean arterial pressure (MAP) and symptoms. Repeated measures of orthostatic haemodynamic parameters (systolic blood pressure, diastolic blood pressure, MAP, heart rate, percentage change of Modelflow parameters), weight, frequency of dizziness, 24-h urinary sodium and volume, 24-h ambulatory blood pressure (24-ABPM) and presence of ankle oedema were collected at baseline and at 6 weeks.
Results: symptoms improved, to a similar extent, in both groups. There were no differences in MAP or other haemodynamic parameters, weight, urinary volume or 24-ABPM between SHU and controls. SHU were more likely to have leg oedema.
Conclusions: these findings suggested that SHU at 6 inches has no additional effects on symptoms or haemodynamic parameters at 6 weeks than existing non-pharmacological measures in older patients with OH. Its use in this group should therefore be discouraged.

• 出版日期2011-3