A chemo-enzymatic approach to specifically click-modified RNA

作者:Dojahn Claudine M; Hesse Marlen; Arenz Christoph*
来源:Chemical Communications, 2013, 49(30): 3128-3130.
DOI:10.1039/c3cc40594j

摘要

The growing interest in single-molecule analysis of RNA calls for programmable enzymatic labeling strategies beyond the horizon of solid-phase synthesized RNAs. Herein we describe an easy and versatile chemo-enzymatic approach to label RNA at its termini or defined internal positions via click-chemistry.

  • 出版日期2013